For healthcare professionals

Melatonin

Melatonin 1 mg/1 mL oral solution, sugar free and alcohol free, strawberry flavour. 1 mL = 1 mg, so the dose in mg equals the volume in mL.

1 mg / 1 mL100 mLOnce at bedtime
Melatonin 1 mg/1 mL oral solution carton and bottle

Patient details

1306090120 kg
kg
Indication
Trials found no extra benefit above 0.05 mg/kg; timing matters more than dose.

How to take

  • Children: 30–60 min before bedtime. Raise by 1 mg weekly to effect, max 5 mg/day.
  • Jet lag: at bedtime on arrival, never before 20:00 or after 04:00 local time. Max 5 days, up to 16 courses a year.
  • No food for 2 h before and after a dose.

Key cautions

  • Avoid with fluvoxamine. Caution with cimetidine, oestrogens, quinolones, warfarin and sedatives.
  • Not recommended in autoimmune disease, pregnancy, breast-feeding, severe renal or moderate–severe hepatic impairment.
  • Contains aspartame (a source of phenylalanine): avoid in phenylketonuria. Also contains propylene glycol and parabens.
  • Review after 3 months; re-check at least every 6 months.

Sources